Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 7109 392 2.1297 1.5833 0.0551 0.0617
MZ7-mel Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 1 3287 185 0.9835 0.8880 0.0563 0.0519
MZ7-mel Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 2 3000 167 0.8982 0.8880 0.0557 0.0519
MZ7-mel Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 3 2580 113 0.7822 0.8880 0.0438 0.0519
MZ7-mel Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 1 4472 217 1.3491 0.9268 0.0485 0.0478
MZ7-mel Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 2 3244 144 0.9829 0.9268 0.0444 0.0478
MZ7-mel Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 3 1489 75 0.4483 0.9268 0.0504 0.0478
MZ7-mel Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 1 2075 115 0.6214 0.7710 0.0554 0.0544
MZ7-mel Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 2 2697 158 0.8050 0.7710 0.0586 0.0544
MZ7-mel Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 3 2941 145 0.8865 0.7710 0.0493 0.0544
MZ7-mel Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 1 2107 125 0.6284 0.8443 0.0593 0.0545
MZ7-mel Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 2 3036 153 0.9141 0.8443 0.0504 0.0545
MZ7-mel Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 3 3302 178 0.9905 0.8443 0.0539 0.0545
MZ7-mel Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 1 2574 151 0.7682 0.5584 0.0587 0.0586
MZ7-mel Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 2 2096 111 0.6294 0.5584 0.0530 0.0586
MZ7-mel Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 3 936 60 0.2777 0.5584 0.0641 0.0586
MZ7-mel Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 1 2958 221 0.8678 0.5805 0.0747 0.0771
MZ7-mel Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 2 1901 140 0.5583 0.5805 0.0736 0.0771
MZ7-mel Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 3 1085 90 0.3155 0.5805 0.0829 0.0771
MZ7-mel Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 1 1462 72 0.4407 0.5486 0.0492 0.0710
MZ7-mel Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 2 1878 154 0.5466 0.5486 0.0820 0.0710
MZ7-mel Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 3 2262 185 0.6585 0.5486 0.0818 0.0710
MZ7-mel Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 1 1203 114 0.3453 0.4369 0.0948 0.0888
MZ7-mel Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 2 1571 141 0.4534 0.4369 0.0898 0.0888
MZ7-mel Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 3 1759 144 0.5120 0.4369 0.0819 0.0888