Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.533 | uM | 7523.074 | 0.7331 | 0.3883 | 0.8505 | |
| MX1 | Unknown | Unknown | Etoposide | TOP2 | TOP | 2.67 | uM | 7523.074 | 0.5258 | -0.0609 | 0.8505 | |
| MX1 | Unknown | Unknown | Etoposide | TOP2 | TOP | 13.3 | uM | 7523.074 | 0.4819 | -0.1524 | 0.8505 | |
| MX1 | Unknown | Unknown | Etoposide | TOP2 | TOP | 66.7 | uM | 7523.074 | 0.1198 | -0.8350 | 0.8505 | |
| MX1 | Unknown | Unknown | Etoposide | TOP2 | TOP | 333 | uM | 7523.074 | 0.0597 | -0.9272 | 0.8505 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7526.074 | 1.0525 | 1.0630 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7526.074 | 1.0199 | 1.0240 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7526.074 | 0.9619 | 0.9535 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7526.074 | 0.9473 | 0.9355 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7526.074 | 0.7948 | 0.7402 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7526.074 | 0.4074 | 0.1608 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7526.074 | 0.1691 | -0.3187 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7526.074 | 0.0649 | -0.6187 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7526.074 | 0.0503 | -0.6732 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7527.074 | 1.0628 | 1.0646 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7527.074 | 1.0210 | 1.0218 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7527.074 | 0.9926 | 0.9922 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7527.074 | 0.9910 | 0.9906 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7527.074 | 0.8232 | 0.8069 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7527.074 | 0.4468 | 0.3136 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7527.074 | 0.2098 | -0.1146 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7527.074 | 0.1089 | -0.3713 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7527.074 | 0.0797 | -0.4657 | 1.9162 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7528.074 | 1.0586 | 1.1154 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7528.074 | 1.0448 | 1.0884 | 1.0143 |