Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7911.017 | 1.0242 | 1.0299 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.011 | uM | 7911.017 | 1.0854 | 1.1041 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7911.017 | 0.9345 | 0.9179 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.276 | uM | 7911.017 | 0.7843 | 0.7206 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 1.38 | uM | 7911.017 | 0.1477 | -0.3880 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 6.9 | uM | 7911.017 | 0.1062 | -0.5011 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 34.5 | uM | 7911.017 | 0.0653 | -0.6308 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 172 | uM | 7911.017 | 0.0001 | -0.9915 | 1.6151 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7861.017 | 0.9792 | 0.9769 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7861.017 | 0.9667 | 0.9628 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7861.017 | 0.9653 | 0.9613 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7861.017 | 0.8592 | 0.8388 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7861.017 | 0.6294 | 0.5479 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7861.017 | 0.1504 | -0.2992 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7861.017 | 0.0823 | -0.4980 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7861.017 | 0.0215 | -0.7611 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7861.017 | 0.0003 | -0.9757 | 1.8068 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7862.017 | 0.8926 | 0.8350 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7862.017 | 0.9913 | 0.9867 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7862.017 | 0.8399 | 0.7524 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7862.017 | 0.9746 | 0.9615 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7862.017 | 0.7264 | 0.5697 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7862.017 | 0.3806 | -0.0380 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7862.017 | 0.0894 | -0.6790 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7862.017 | 0.0724 | -0.7265 | 1.3198 |