Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 66.7 | uM | 10873.156 | 0.0237 | -0.9065 | 1.2215 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.000171 | uM | 12400.164 | 1.0335 | 1.0520 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.000853 | uM | 12400.164 | 0.9077 | 0.8546 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.00427 | uM | 12400.164 | 0.8810 | 0.8121 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.0213 | uM | 12400.164 | 0.7119 | 0.5348 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.107 | uM | 12400.164 | 0.6193 | 0.3768 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.533 | uM | 12400.164 | 0.5747 | 0.2989 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 2.67 | uM | 12400.164 | 0.5360 | 0.2303 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 13.3 | uM | 12400.164 | 0.5048 | 0.1741 | 1.2834 | |
| HCC70 | TNBC | Basal A | Everolimus | MTOR | MTOR | 66.7 | uM | 12400.164 | 0.0136 | -0.9299 | 1.2834 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12319.156 | 0.9281 | 0.8801 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12319.156 | 0.7993 | 0.6613 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12319.156 | 0.9096 | 0.8491 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12319.156 | 0.7832 | 0.6334 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12319.156 | 0.5300 | 0.1820 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12319.156 | 0.6200 | 0.3459 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12319.156 | 0.4702 | 0.0703 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12319.156 | 0.4913 | 0.1101 | 1.2070 | |
| LY2 | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12319.156 | 0.3371 | -0.1875 | 1.2070 | |
| MB 157 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.000171 | uM | 12580.164 | 0.9131 | 0.9150 | 2.0914 | |
| MB 157 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.000853 | uM | 12580.164 | 0.7519 | 0.7451 | 2.0914 | |
| MB 157 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.00427 | uM | 12580.164 | 0.6403 | 0.6161 | 2.0914 | |
| MB 157 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.0213 | uM | 12580.164 | 0.5527 | 0.5063 | 2.0914 | |
| MB 157 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.107 | uM | 12580.164 | 0.5249 | 0.4695 | 2.0914 | |
| MB 157 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.533 | uM | 12580.164 | 0.5245 | 0.4691 | 2.0914 |