Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 7505.078 | 0.4444 | 0.0086 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 7505.078 | 0.2367 | -0.4074 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 7505.078 | 0.2593 | -0.3601 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 7505.078 | 0.0052 | -0.9764 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7896.007 | 0.9923 | 0.9863 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7896.007 | 1.0514 | 1.0915 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7896.007 | 1.0080 | 1.0143 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7896.007 | 0.9266 | 0.8685 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7896.007 | 0.8567 | 0.7421 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7896.007 | 0.4061 | -0.1053 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7896.007 | 0.2109 | -0.5015 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7896.007 | 0.2388 | -0.4430 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7896.007 | 0.0122 | -0.9610 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7896.043 | 1.0406 | 1.0953 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7896.043 | 0.9445 | 0.8709 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7896.043 | 0.9919 | 0.9811 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7896.043 | 0.9761 | 0.9441 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7896.043 | 1.0117 | 1.0274 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7896.043 | 0.9257 | 0.8274 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7896.043 | 0.8355 | 0.6211 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7896.043 | 0.4210 | -0.2726 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7896.043 | 0.2899 | -0.5297 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9648.121 | 1.0552 | 1.1712 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9648.121 | 1.0274 | 1.0844 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9648.121 | 0.9249 | 0.7750 | 0.6537 |