Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7833.007 | 1.0302 | 1.0465 | 1.2952 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10262.034 | 1.0019 | 1.0059 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10262.034 | 0.9547 | 0.8650 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10262.034 | 0.9870 | 0.9611 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10262.034 | 0.9514 | 0.8554 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10262.034 | 0.9209 | 0.7663 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.69 | uM | 10262.034 | 0.6887 | 0.1401 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 3.45 | uM | 10262.034 | 0.3605 | -0.5704 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 17.2 | uM | 10262.034 | 0.3050 | -0.6660 | 0.6634 | |
| HCC1937 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10262.034 | 0.1736 | -0.8572 | 0.6634 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7837.007 | 1.0473 | 1.0570 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7837.007 | 0.9594 | 0.9502 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7837.007 | 1.0038 | 1.0047 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7837.007 | 0.8013 | 0.7478 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7837.007 | 0.8235 | 0.7771 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7837.007 | 0.2303 | -0.1816 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7837.007 | 0.2542 | -0.1308 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7837.007 | 0.0247 | -0.7897 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7837.007 | 0.0055 | -0.9154 | 1.6436 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9386.121 | 1.0950 | 1.1609 | 1.1728 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9386.121 | 1.0857 | 1.1452 | 1.1728 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9386.121 | 1.1109 | 1.1876 | 1.1728 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9386.121 | 0.9647 | 0.9397 | 1.1728 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9386.121 | 0.8197 | 0.6881 | 1.1728 | |
| HCC1954 | HER2amp | Basal A | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9386.121 | 0.3103 | -0.2626 | 1.1728 |