Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 9158.121 | 0.0049 | -0.9861 | 1.0691 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9163.121 | 1.0411 | 1.1924 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9163.121 | 0.9929 | 0.9676 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9163.121 | 1.1146 | 1.5621 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9163.121 | 1.0376 | 1.1756 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9163.121 | 0.9546 | 0.7990 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9163.121 | 0.1577 | -0.9704 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9163.121 | 0.5305 | -0.5292 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9163.121 | 0.4720 | -0.6394 | 0.4382 | |
| BT-474 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 9163.121 | 0.0062 | -1.0000 | 0.4382 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7801.007 | 0.9612 | 0.8808 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7801.007 | 0.9670 | 0.8987 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7801.007 | 0.9114 | 0.7318 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7801.007 | 0.9345 | 0.8004 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7801.007 | 0.8588 | 0.5792 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7801.007 | 0.6947 | 0.1365 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7801.007 | 0.3478 | -0.6114 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7801.007 | 0.5975 | -0.1004 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7801.007 | 0.2734 | -0.7325 | 0.6446 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9186.121 | 1.0170 | 1.0407 | 0.8379 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9186.121 | 0.9731 | 0.9360 | 0.8379 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9186.121 | 0.9955 | 0.9893 | 0.8379 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9186.121 | 0.9670 | 0.9215 | 0.8379 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9186.121 | 0.9783 | 0.9482 | 0.8379 | |
| BT-483 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9186.121 | 0.6693 | 0.2385 | 0.8379 |