Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9844.002 | 0.1047 | -0.2007 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9844.002 | 0.0993 | -0.2175 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 9844.002 | 0.1272 | -0.1348 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 9844.002 | 0.1237 | -0.1446 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13004.002 | 0.9077 | 0.9392 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13004.002 | 1.0238 | 1.0150 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13004.002 | 0.6798 | 0.7686 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13004.002 | 0.2098 | 0.2160 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 13004.002 | 0.0905 | -0.0696 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 13004.002 | 0.0798 | -0.1063 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 13004.002 | 0.0852 | -0.0875 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 13004.002 | 0.0906 | -0.0693 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 13004.002 | 0.0945 | -0.0568 | 3.1387 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13054.002 | 0.9396 | 0.9597 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13054.002 | 1.0054 | 1.0035 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13054.002 | 0.4871 | 0.5807 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13054.002 | 0.1339 | 0.0363 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 13054.002 | 0.0808 | -0.1215 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 13054.002 | 0.0832 | -0.1131 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 13054.002 | 0.0858 | -0.1041 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 13054.002 | 0.0831 | -0.1135 | 3.0574 | |
| SUM159PT | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 13054.002 | 0.0850 | -0.1071 | 3.0574 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7921.002 | 0.9969 | 0.9913 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7921.002 | 0.9946 | 0.9850 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7921.002 | 1.0170 | 1.0475 | 0.7161 |