Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
BT-483
HR+
Luminal
Docetaxel
TUBB
TUBB
10
uM
9186.002
0.7467 0.0839 0.4768
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.0000256
uM
10261.002
1.0370 1.0333 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.000128
uM
10261.002
1.0372 1.0335 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.00064
uM
10261.002
1.0263 1.0238 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.0032
uM
10261.002
0.7553 0.7603 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.016
uM
10261.002
0.3630 0.2613 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.08
uM
10261.002
0.2624 0.0882 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.4
uM
10261.002
0.2391 0.0431 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
2
uM
10261.002
0.3137 0.1803 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
10
uM
10261.002
0.3511 0.2423 2.1983
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.0000256
uM
12690.002
0.9699 0.9751 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.000128
uM
12690.002
0.9625 0.9689 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.00064
uM
12690.002
0.8583 0.8786 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.0032
uM
12690.002
0.4389 0.4270 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.016
uM
12690.002
0.2374 0.1094 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.08
uM
12690.002
0.1956 0.0247 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
0.4
uM
12690.002
0.1940 0.0212 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
2
uM
12690.002
0.2373 0.1091 2.4397
BT-549
TNBC
Basal B
Docetaxel
TUBB
TUBB
10
uM
12690.002
0.2363 0.1072 2.4397
CAMA-1
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0000256
uM
9210.002
1.0294 1.0658 0.8958
CAMA-1
HR+
Luminal
Docetaxel
TUBB
TUBB
0.000128
uM
9210.002
0.9528 0.8949 0.8958
CAMA-1
HR+
Luminal
Docetaxel
TUBB
TUBB
0.00064
uM
9210.002
0.9560 0.9019 0.8958
CAMA-1
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0032
uM
9210.002
0.9339 0.8529 0.8958
CAMA-1
HR+
Luminal
Docetaxel
TUBB
TUBB
0.016
uM
9210.002
0.3829 -0.3152 0.8958
CAMA-1
HR+
Luminal
Docetaxel
TUBB
TUBB
0.08
uM
9210.002
0.3946 -0.2917 0.8958