Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-483 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9186.002 | 0.7467 | 0.0839 | 0.4768 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10261.002 | 1.0370 | 1.0333 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10261.002 | 1.0372 | 1.0335 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10261.002 | 1.0263 | 1.0238 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10261.002 | 0.7553 | 0.7603 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 10261.002 | 0.3630 | 0.2613 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 10261.002 | 0.2624 | 0.0882 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 10261.002 | 0.2391 | 0.0431 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 10261.002 | 0.3137 | 0.1803 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 10261.002 | 0.3511 | 0.2423 | 2.1983 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12690.002 | 0.9699 | 0.9751 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12690.002 | 0.9625 | 0.9689 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12690.002 | 0.8583 | 0.8786 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12690.002 | 0.4389 | 0.4270 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 12690.002 | 0.2374 | 0.1094 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 12690.002 | 0.1956 | 0.0247 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 12690.002 | 0.1940 | 0.0212 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 12690.002 | 0.2373 | 0.1091 | 2.4397 | |
BT-549 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 12690.002 | 0.2363 | 0.1072 | 2.4397 | |
CAMA-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9210.002 | 1.0294 | 1.0658 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9210.002 | 0.9528 | 0.8949 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9210.002 | 0.9560 | 0.9019 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9210.002 | 0.9339 | 0.8529 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9210.002 | 0.3829 | -0.3152 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9210.002 | 0.3946 | -0.2917 | 0.8958 |