Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.000256 | uM | 10695.145 | 0.9819 | 0.9681 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.00128 | uM | 10695.145 | 0.9609 | 0.9309 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.0064 | uM | 10695.145 | 0.9293 | 0.8750 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.032 | uM | 10695.145 | 1.0130 | 1.0229 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.16 | uM | 10695.145 | 0.9948 | 0.9909 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.8 | uM | 10695.145 | 0.7702 | 0.5893 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 4 | uM | 10695.145 | 0.3696 | -0.1672 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 20 | uM | 10695.145 | 0.1430 | -0.6390 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 100 | uM | 10695.145 | 0.0251 | -0.9219 | 1.1360 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.000256 | uM | 11852.145 | 0.9220 | 0.8983 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.00128 | uM | 11852.145 | 0.9942 | 0.9925 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.0064 | uM | 11852.145 | 0.9350 | 0.9153 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.032 | uM | 11852.145 | 0.9232 | 0.8999 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.16 | uM | 11852.145 | 0.9394 | 0.9212 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 0.8 | uM | 11852.145 | 0.7702 | 0.6908 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 4 | uM | 11852.145 | 0.5363 | 0.3397 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 20 | uM | 11852.145 | 0.3718 | 0.0586 | 1.5550 | |
| SUM52PE | HR+ | Luminal | Bosutinib | Src | nRTK | 100 | uM | 11852.145 | 0.3605 | 0.0377 | 1.5550 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 0.000256 | uM | 10939.145 | 1.0143 | 1.0172 | 1.6558 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 0.00128 | uM | 10939.145 | 1.0096 | 1.0116 | 1.6558 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 0.0064 | uM | 10939.145 | 0.9643 | 0.9565 | 1.6558 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 0.032 | uM | 10939.145 | 0.9342 | 0.9194 | 1.6558 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 0.16 | uM | 10939.145 | 1.0068 | 1.0082 | 1.6558 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 0.8 | uM | 10939.145 | 0.9659 | 0.9586 | 1.6558 | |
| T47D | HR+ | Luminal | Bosutinib | Src | nRTK | 4 | uM | 10939.145 | 0.8175 | 0.7708 | 1.6558 |