Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.032 | uM | 10999.145 | 0.9428 | 0.8512 | 0.7621 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.16 | uM | 10999.145 | 0.9960 | 0.9895 | 0.7621 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.8 | uM | 10999.145 | 0.8806 | 0.6926 | 0.7621 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 4 | uM | 10999.145 | 0.5716 | -0.0400 | 0.7621 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 20 | uM | 10999.145 | 0.4898 | -0.2162 | 0.7621 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 100 | uM | 10999.145 | 0.4896 | -0.2166 | 0.7621 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.0000853 | uM | 12379.17 | 1.0063 | 1.0216 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.000427 | uM | 12379.17 | 0.9954 | 0.9843 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.00213 | uM | 12379.17 | 0.9947 | 0.9817 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.0107 | uM | 12379.17 | 1.0259 | 1.0902 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.0533 | uM | 12379.17 | 1.0833 | 1.2956 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 0.267 | uM | 12379.17 | 0.9936 | 0.9779 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 1.33 | uM | 12379.17 | 0.8154 | 0.4073 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 6.67 | uM | 12379.17 | 0.3585 | -0.6583 | 0.5805 | |
MDA-MB-361 | HER2amp | Luminal | Bosutinib | Src | nRTK | 33.3 | uM | 12379.17 | 0.3697 | -0.6398 | 0.5805 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.000256 | uM | 10938.145 | 0.8123 | 0.6577 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.00128 | uM | 10938.145 | 0.7501 | 0.5426 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.0064 | uM | 10938.145 | 0.8147 | 0.6622 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.032 | uM | 10938.145 | 0.7969 | 0.6292 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.16 | uM | 10938.145 | 0.9079 | 0.8330 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.8 | uM | 10938.145 | 0.5381 | 0.1429 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 4 | uM | 10938.145 | 0.7493 | 0.5411 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 20 | uM | 10938.145 | 0.0891 | -0.7748 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 100 | uM | 10938.145 | 0.5076 | 0.0842 | 1.1073 | |
MDA-MB-415 | HR+ | Luminal | Bosutinib | Src | nRTK | 0.0000853 | uM | 12333.17 | 0.9212 | 0.7689 | 0.6683 |