Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.032
uM
10999.145
0.9428 0.8512 0.7621
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.16
uM
10999.145
0.9960 0.9895 0.7621
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.8
uM
10999.145
0.8806 0.6926 0.7621
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
4
uM
10999.145
0.5716 -0.0400 0.7621
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
20
uM
10999.145
0.4898 -0.2162 0.7621
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
100
uM
10999.145
0.4896 -0.2166 0.7621
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.0000853
uM
12379.17
1.0063 1.0216 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.000427
uM
12379.17
0.9954 0.9843 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.00213
uM
12379.17
0.9947 0.9817 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.0107
uM
12379.17
1.0259 1.0902 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.0533
uM
12379.17
1.0833 1.2956 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
0.267
uM
12379.17
0.9936 0.9779 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
1.33
uM
12379.17
0.8154 0.4073 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
6.67
uM
12379.17
0.3585 -0.6583 0.5805
MDA-MB-361
HER2amp
Luminal
Bosutinib
Src
nRTK
33.3
uM
12379.17
0.3697 -0.6398 0.5805
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.000256
uM
10938.145
0.8123 0.6577 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.00128
uM
10938.145
0.7501 0.5426 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.0064
uM
10938.145
0.8147 0.6622 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.032
uM
10938.145
0.7969 0.6292 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.16
uM
10938.145
0.9079 0.8330 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.8
uM
10938.145
0.5381 0.1429 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
4
uM
10938.145
0.7493 0.5411 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
20
uM
10938.145
0.0891 -0.7748 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
100
uM
10938.145
0.5076 0.0842 1.1073
MDA-MB-415
HR+
Luminal
Bosutinib
Src
nRTK
0.0000853
uM
12333.17
0.9212 0.7689 0.6683