Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-134-VI	HR+	Luminal	Bosutinib	Src	nRTK	20	uM	12206.145	0.6489	0.2171	0.8709
MDA-MB-134-VI	HR+	Luminal	Bosutinib	Src	nRTK	100	uM	12206.145	0.7798	0.5031	0.8709
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	0.0000853	uM	12594.17	0.9749	0.9587	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	0.000427	uM	12594.17	0.9840	0.9737	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	0.00213	uM	12594.17	1.0135	1.0221	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	0.0107	uM	12594.17	0.9796	0.9664	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	0.0533	uM	12594.17	1.0856	1.1395	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	0.267	uM	12594.17	1.1847	1.2985	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	1.33	uM	12594.17	0.7084	0.5070	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	6.67	uM	12594.17	0.1087	-0.6767	1.2180
MDA-MB-157	TNBC	Basal B	Bosutinib	Src	nRTK	33.3	uM	12594.17	0.1095	-0.6747	1.2180
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.000256	uM	10642.145	0.9932	0.9615	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.00128	uM	10642.145	1.0027	1.0155	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.0064	uM	10642.145	0.9848	0.9155	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.032	uM	10642.145	0.9794	0.8856	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.16	uM	10642.145	1.0930	1.5715	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.8	uM	10642.145	0.8213	0.1462	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	4	uM	10642.145	0.7244	-0.1960	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	20	uM	10642.145	0.4967	-0.7233	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	100	uM	10642.145	0.4863	-0.7394	0.3537
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.000256	uM	10818.145	0.9670	0.8598	0.4621
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.00128	uM	10818.145	0.9411	0.7540	0.4621
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.0064	uM	10818.145	0.9709	0.8763	0.4621
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.032	uM	10818.145	1.0122	1.0534	0.4621
MDA-MB-175-VII	HR+	Luminal	Bosutinib	Src	nRTK	0.16	uM	10818.145	0.9673	0.8613	0.4621

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)