Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7534.074 | 0.9884 | 0.9789 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7534.074 | 0.9884 | 0.9789 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7534.074 | 0.5785 | 0.2173 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7534.074 | 0.5785 | 0.2173 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7534.074 | 0.3513 | -0.2256 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7534.074 | 0.3513 | -0.2256 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7534.074 | 0.2349 | -0.4624 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7534.074 | 0.2349 | -0.4624 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7534.074 | 0.1748 | -0.5888 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7534.074 | 0.1748 | -0.5888 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7534.074 | 0.1371 | -0.6700 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7534.074 | 0.1371 | -0.6700 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7534.074 | 0.1227 | -0.7017 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7534.074 | 0.1227 | -0.7017 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14803.203 | 1.0415 | 1.0578 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14803.203 | 1.0415 | 1.0578 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14803.203 | 1.1360 | 1.1866 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14803.203 | 1.1360 | 1.1866 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14803.203 | 0.6229 | 0.4360 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14803.203 | 0.6229 | 0.4360 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14803.203 | 0.4024 | 0.0577 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14803.203 | 0.4024 | 0.0577 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14803.203 | 0.3221 | -0.0949 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14803.203 | 0.3221 | -0.0949 | 1.4290 | |
| SUM225CWN | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14803.203 | 0.2688 | -0.2025 | 1.4290 |