Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14918.203 | 0.5400 | -0.3752 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14918.203 | 0.5400 | -0.3752 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14918.203 | 0.1168 | -0.9653 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14918.203 | 0.1168 | -0.9653 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14918.203 | 0.0388 | -0.9957 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14918.203 | 0.0388 | -0.9957 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14918.203 | 0.0194 | -0.9988 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14918.203 | 0.0194 | -0.9988 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14918.203 | 0.0149 | -0.9993 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14918.203 | 0.0149 | -0.9993 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14918.203 | 0.0136 | -0.9994 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14918.203 | 0.0136 | -0.9994 | 0.5296 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7526.074 | 1.0192 | 1.0232 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7526.074 | 1.0192 | 1.0232 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7526.074 | 0.9978 | 0.9973 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7526.074 | 0.9978 | 0.9973 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7526.074 | 0.9965 | 0.9957 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7526.074 | 0.9965 | 0.9957 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7526.074 | 0.9220 | 0.9039 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7526.074 | 0.9220 | 0.9039 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7526.074 | 0.1478 | -0.3719 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7526.074 | 0.1478 | -0.3719 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7526.074 | 0.1057 | -0.4874 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7526.074 | 0.1057 | -0.4874 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7526.074 | 0.0672 | -0.6105 | 1.6506 |