Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9797.019 | 1.0260 | 1.1071 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9797.019 | 1.0105 | 1.0431 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9797.019 | 1.0297 | 1.1229 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9797.019 | 0.9973 | 0.9888 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9797.019 | 1.0680 | 1.2867 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9797.019 | 1.0573 | 1.2401 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9797.019 | 0.9903 | 0.9606 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9797.019 | 0.8726 | 0.5156 | 0.4912 | ||
| SUM1315MO2 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9797.019 | 0.0298 | -0.9984 | 0.4912 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7917.016 | 1.0375 | 1.0251 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7917.016 | 1.0130 | 1.0087 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7917.016 | 0.9567 | 0.9703 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7917.016 | 0.9825 | 0.9881 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7917.016 | 1.0490 | 1.0327 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7917.016 | 1.0012 | 1.0008 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7917.016 | 0.8512 | 0.8938 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7917.016 | 0.9171 | 0.9422 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7917.016 | 0.5580 | 0.6414 | 2.9532 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9830.019 | 1.1103 | 1.1129 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9830.019 | 1.0041 | 1.0044 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9830.019 | 1.0926 | 1.0952 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9830.019 | 1.0003 | 1.0003 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9830.019 | 1.0410 | 1.0426 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9830.019 | 1.0005 | 1.0005 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9830.019 | 0.8830 | 0.8735 | 1.9053 |