Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7875.016 | 0.9260 | 0.9074 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7875.016 | 0.9348 | 0.9186 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7875.016 | 0.9086 | 0.8853 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7875.016 | 0.9220 | 0.9024 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7875.016 | 0.7556 | 0.6829 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7875.016 | 0.7674 | 0.6990 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7875.016 | 0.2754 | -0.0965 | 1.6229 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9583.132 | 1.0477 | 1.0787 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9583.132 | 0.9657 | 0.9430 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9583.132 | 1.0278 | 1.0459 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9583.132 | 0.9871 | 0.9786 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9583.132 | 0.9731 | 0.9553 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9583.132 | 1.0141 | 1.0233 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9583.132 | 0.9159 | 0.8596 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9583.132 | 0.9796 | 0.9661 | 1.2070 | ||
| MCF7 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9583.132 | 0.9644 | 0.9409 | 1.2070 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7876.016 | 0.9869 | 0.9752 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7876.016 | 0.9685 | 0.9403 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7876.016 | 0.9102 | 0.8299 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7876.016 | 0.8583 | 0.7311 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7876.016 | 0.8776 | 0.7678 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7876.016 | 0.8113 | 0.6413 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7876.016 | 0.7157 | 0.4580 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7876.016 | 0.8062 | 0.6316 | 1.0580 | ||
| MDA-MB-134-VI | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7876.016 | 0.7661 | 0.5547 | 1.0580 |