Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9830.019 | 0.7032 | 0.6625 | 1.9053 | ||
| SUM149PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9830.019 | 0.0088 | -0.8334 | 1.9053 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7918.016 | 1.1828 | 1.1106 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7918.016 | 0.7010 | 0.7847 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7918.016 | 1.0312 | 1.0198 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7918.016 | 0.9861 | 0.9911 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7918.016 | 1.1134 | 1.0701 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7918.016 | 1.0060 | 1.0038 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7918.016 | 0.5194 | 0.6211 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7918.016 | 0.9161 | 0.9446 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7918.016 | 0.0116 | -0.5212 | 3.1190 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7919.016 | 0.9955 | 0.9975 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7919.016 | 0.9882 | 0.9933 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7919.016 | 0.9756 | 0.9861 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7919.016 | 0.9997 | 0.9998 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7919.016 | 1.0354 | 1.0197 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7919.016 | 1.0039 | 1.0022 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7919.016 | 0.8406 | 0.9045 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7919.016 | 0.5134 | 0.6576 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7919.016 | 0.9457 | 0.9688 | 3.5497 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7920.016 | 1.1144 | 1.0507 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7920.016 | 1.0702 | 1.0316 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7920.016 | 1.1169 | 1.0518 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7920.016 | 1.1259 | 1.0556 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7920.016 | 1.0504 | 1.0229 | 4.3230 |