Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7432.074 | 0.0819 | -0.8911 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7432.074 | 0.0050 | -0.9958 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7432.074 | 0.0050 | -0.9958 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7432.074 | 0.0009 | -0.9994 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7432.074 | 0.0009 | -0.9994 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7432.074 | 0.0003 | -0.9998 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7432.074 | 0.0003 | -0.9998 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7432.074 | 0.0024 | -0.9982 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7432.074 | 0.0024 | -0.9982 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7432.074 | 0.0010 | -0.9993 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7432.074 | 0.0010 | -0.9993 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15300.203 | 0.9438 | 0.8675 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15300.203 | 0.9438 | 0.8675 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15300.203 | 0.8547 | 0.6606 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15300.203 | 0.8547 | 0.6606 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15300.203 | 0.1498 | -0.7888 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15300.203 | 0.1498 | -0.7888 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15300.203 | 0.0115 | -0.9899 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15300.203 | 0.0115 | -0.9899 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15300.203 | 0.0091 | -0.9924 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15300.203 | 0.0091 | -0.9924 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15300.203 | 0.0103 | -0.9911 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15300.203 | 0.0103 | -0.9911 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15300.203 | 0.0069 | -0.9945 | 0.8443 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15300.203 | 0.0069 | -0.9945 | 0.8443 |