Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14646.189 | 0.9993 | 0.9988 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14646.189 | 0.9096 | 0.8292 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14646.189 | 0.9076 | 0.8254 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14646.189 | 0.7515 | 0.5283 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14646.189 | 0.1727 | -0.6173 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14646.189 | 0.0661 | -0.8450 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14646.189 | 0.1164 | -0.7360 | 1.0620 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14278.189 | 0.9695 | 0.9169 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14278.189 | 0.9189 | 0.7811 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14278.189 | 0.9683 | 0.9137 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14278.189 | 0.9527 | 0.8714 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14278.189 | 0.9473 | 0.8570 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14278.189 | 0.9156 | 0.7724 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14278.189 | 0.1107 | -0.9021 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14278.189 | 0.0250 | -0.9873 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14278.189 | 0.0206 | -0.9902 | 0.7296 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14649.189 | 0.9901 | 0.9652 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14649.189 | 0.9661 | 0.8824 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14649.189 | 1.0184 | 1.0652 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14649.189 | 0.9780 | 0.9233 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14649.189 | 0.9980 | 0.9929 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14649.189 | 0.9405 | 0.7958 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14649.189 | 0.0955 | -0.9677 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14649.189 | 0.0192 | -0.9981 | 0.5692 | |
| MX1 | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14649.189 | 0.0159 | -0.9986 | 0.5692 |