Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14619.189 | 0.9930 | 0.9890 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14619.189 | 0.9437 | 0.9113 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14619.189 | 0.0645 | -0.7655 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14619.189 | 0.0322 | -0.8637 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14619.189 | 0.0345 | -0.8564 | 1.2787 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14272.189 | 0.9957 | 0.9833 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14272.189 | 0.9850 | 0.9416 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14272.189 | 1.0219 | 1.0868 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14272.189 | 0.9809 | 0.9256 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14272.189 | 0.9971 | 0.9886 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14272.189 | 1.0054 | 1.0212 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14272.189 | 0.7359 | 0.0955 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14272.189 | 0.1164 | -0.9706 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14272.189 | 0.3983 | -0.6717 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14643.189 | 0.9454 | 0.8735 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14643.189 | 0.9556 | 0.8971 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14643.189 | 0.9814 | 0.9568 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14643.189 | 0.9594 | 0.9059 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14643.189 | 0.9703 | 0.9311 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14643.189 | 0.9847 | 0.9645 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14643.189 | 0.7438 | 0.4178 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14643.189 | 0.1290 | -0.8149 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14643.189 | 0.0436 | -0.9475 | 0.8604 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14646.189 | 0.8925 | 0.7970 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14646.189 | 0.9103 | 0.8307 | 1.0620 |