Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10874.151 | 1.0039 | 1.0105 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.213 | uM | 10874.151 | 0.9889 | 0.9703 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 1.07 | uM | 10874.151 | 0.2114 | -0.7499 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 5.33 | uM | 10874.151 | 0.1728 | -0.8089 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 26.7 | uM | 10874.151 | 0.1270 | -0.8735 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 133 | uM | 10874.151 | 0.2645 | -0.6623 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12220.157 | 1.0231 | 1.1422 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12220.157 | 1.0599 | 1.3822 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12220.157 | 1.0084 | 1.0507 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12220.157 | 1.1195 | 1.8086 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.213 | uM | 12220.157 | 1.0902 | 1.5934 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 1.07 | uM | 12220.157 | 0.7423 | -0.1837 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 5.33 | uM | 12220.157 | 0.3270 | -0.9306 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 26.7 | uM | 12220.157 | 0.4045 | -0.8685 | 0.3325 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 133 | uM | 12220.157 | 0.4583 | -0.8085 | 0.3325 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11851.157 | 0.9047 | 0.8684 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11851.157 | 0.9686 | 0.9571 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11851.157 | 0.9619 | 0.9479 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11851.157 | 0.9725 | 0.9624 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11851.157 | 0.9160 | 0.8842 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11851.157 | 0.9627 | 0.9489 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11851.157 | 0.3532 | -0.0144 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11851.157 | 0.3454 | -0.0293 | 1.4707 | |
| SK-BR-3 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11851.157 | 0.4078 | 0.0868 | 1.4707 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10875.151 | 0.9824 | 0.9507 | 0.7096 |