Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12333.157 | 0.7625 | 0.3994 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12333.157 | 0.5289 | -0.1359 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12333.157 | 0.5147 | -0.1662 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12333.157 | 0.6014 | 0.0236 | 0.7591 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12414.157 | 0.9581 | 0.9193 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12414.157 | 0.9334 | 0.8716 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12414.157 | 0.9900 | 0.9807 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12414.157 | 0.9793 | 0.9601 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12414.157 | 0.9718 | 0.9457 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12414.157 | 0.6694 | 0.3592 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12414.157 | 0.3017 | -0.3687 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12414.157 | 0.2847 | -0.4029 | 1.0392 | |
| MDA-MB-453 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12414.157 | 0.7399 | 0.4968 | 1.0392 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10644.139 | 0.9634 | 0.8808 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10644.139 | 0.9655 | 0.8877 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10644.139 | 0.9742 | 0.9158 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10644.139 | 0.9272 | 0.7662 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.213 | uM | 10644.139 | 0.9682 | 0.8963 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 1.07 | uM | 10644.139 | 0.6469 | -0.0234 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 5.33 | uM | 10644.139 | 0.0892 | -0.9625 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 26.7 | uM | 10644.139 | 0.0860 | -0.9647 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 133 | uM | 10644.139 | 0.0831 | -0.9667 | 0.6077 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10874.151 | 1.0171 | 1.0458 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10874.151 | 1.0310 | 1.0833 | 0.7476 | |
| MX1 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10874.151 | 1.0211 | 1.0567 | 0.7476 |