Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10999.151 | 0.5059 | -0.2351 | 0.7090 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10999.151 | 0.5485 | -0.1427 | 0.7090 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12379.157 | 1.0863 | 1.3671 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12379.157 | 1.0993 | 1.4252 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12379.157 | 1.0386 | 1.1604 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12379.157 | 1.0633 | 1.2665 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12379.157 | 1.0655 | 1.2757 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12379.157 | 0.7972 | 0.2606 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12379.157 | 0.4622 | -0.5846 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12379.157 | 0.5919 | -0.3126 | 0.4910 | |
| MDA-MB-361 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12379.157 | 0.4832 | -0.5453 | 0.4910 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10938.151 | 0.9010 | 0.8150 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10938.151 | 0.8876 | 0.7900 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10938.151 | 0.8896 | 0.7938 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10938.151 | 0.8562 | 0.7309 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10938.151 | 0.8728 | 0.7622 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10938.151 | 0.5750 | 0.1952 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10938.151 | 0.6242 | 0.2899 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10938.151 | 0.5297 | 0.1072 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10938.151 | 0.5251 | 0.0984 | 1.0747 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12333.157 | 0.8785 | 0.6863 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12333.157 | 0.8542 | 0.6252 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12333.157 | 0.9585 | 0.8913 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12333.157 | 0.9382 | 0.8388 | 0.7591 | |
| MDA-MB-415 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12333.157 | 0.8647 | 0.6514 | 0.7591 |