Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10816.151 | 1.0203 | 1.0420 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10816.151 | 1.0880 | 1.1822 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10816.151 | 0.9461 | 0.8887 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10816.151 | 1.0395 | 1.0816 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10816.151 | 0.3822 | -0.2602 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10816.151 | 0.3197 | -0.3848 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10816.151 | 0.2947 | -0.4345 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10816.151 | 0.2863 | -0.4513 | 0.9672 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12319.157 | 0.8904 | 0.7819 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12319.157 | 0.9786 | 0.9574 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12319.157 | 1.0480 | 1.0954 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12319.157 | 1.0796 | 1.1583 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12319.157 | 0.7871 | 0.5763 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12319.157 | 1.0599 | 1.1191 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12319.157 | 0.2292 | -0.5378 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12319.157 | 0.2420 | -0.5120 | 1.0058 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12319.157 | 0.3057 | -0.3845 | 1.0058 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12580.171 | 0.9876 | 0.9877 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12580.171 | 0.9980 | 0.9980 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12580.171 | 0.9926 | 0.9927 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12580.171 | 1.0015 | 1.0015 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.213 | uM | 12580.171 | 0.9600 | 0.9602 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 1.07 | uM | 12580.171 | 0.6593 | 0.6285 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 5.33 | uM | 12580.171 | 0.2642 | 0.0372 | 2.0272 | |
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 26.7 | uM | 12580.171 | 0.2463 | 0.0019 | 2.0272 |