Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10873.151 | 1.0509 | 1.0860 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 10873.151 | 1.0033 | 1.0055 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 10873.151 | 0.6837 | 0.4485 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10873.151 | 0.2937 | -0.2927 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10873.151 | 0.4300 | -0.0227 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10873.151 | 0.2242 | -0.4376 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12400.157 | 0.9167 | 0.8594 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12400.157 | 0.9085 | 0.8455 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12400.157 | 0.9601 | 0.9330 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12400.157 | 0.9296 | 0.8813 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 12400.157 | 0.9234 | 0.8708 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 12400.157 | 0.7258 | 0.5290 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 12400.157 | 0.3720 | -0.1267 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 12400.157 | 0.6881 | 0.4621 | 1.1935 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 12400.157 | 0.7156 | 0.5109 | 1.1935 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10694.151 | 1.0689 | 1.0555 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10694.151 | 0.9672 | 0.9728 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10694.151 | 1.0177 | 1.0145 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10694.151 | 0.9979 | 0.9982 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 10694.151 | 1.0121 | 1.0099 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 10694.151 | 0.4748 | 0.4728 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 10694.151 | 0.2645 | 0.1581 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 10694.151 | 0.2451 | 0.1224 | 2.4341 | |
| Hs 578T | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 10694.151 | 0.2537 | 0.1385 | 2.4341 | |
| LY2 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10816.151 | 1.0316 | 1.0654 | 0.9672 |