Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 750 | uM | 7544.065 | 0.0288 | -0.8877 | 1.2323 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 3750 | uM | 7544.065 | 0.0170 | -0.9267 | 1.2323 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 18700 | uM | 7544.065 | 0.0140 | -0.9372 | 1.2323 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 0.048 | uM | 7545.065 | 1.0737 | 1.1505 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 0.24 | uM | 7545.065 | 1.0222 | 1.0452 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 1.2 | uM | 7545.065 | 0.9907 | 0.9811 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 6 | uM | 7545.065 | 1.0718 | 1.1466 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 30 | uM | 7545.065 | 0.9975 | 0.9950 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 150 | uM | 7545.065 | 0.5410 | 0.0688 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 750 | uM | 7545.065 | 0.0208 | -0.9615 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 3750 | uM | 7545.065 | 0.0165 | -0.9697 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 18700 | uM | 7545.065 | 0.0151 | -0.9722 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 0.048 | uM | 7546.065 | 0.9711 | 0.9306 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 0.24 | uM | 7546.065 | 1.0063 | 1.0152 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 1.2 | uM | 7546.065 | 0.9875 | 0.9698 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 6 | uM | 7546.065 | 0.9655 | 0.9172 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 30 | uM | 7546.065 | 0.8693 | 0.6895 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 150 | uM | 7546.065 | 0.5420 | -0.0439 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 750 | uM | 7546.065 | 0.0863 | -0.8955 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 3750 | uM | 7546.065 | 0.0403 | -0.9583 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Vorinostat | HDAC | HDAC | 18700 | uM | 7546.065 | 0.0172 | -0.9850 | 0.8300 | |
| UACC-812 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 0.048 | uM | 7547.065 | 0.9431 | 0.8839 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 0.24 | uM | 7547.065 | 0.7393 | 0.4698 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 1.2 | uM | 7547.065 | 0.8858 | 0.7674 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Vorinostat | HDAC | HDAC | 6 | uM | 7547.065 | 0.8775 | 0.7506 | 0.9808 |