Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7495.065 | 0.9596 | 0.9357 | 1.2645 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7495.065 | 0.9679 | 0.9490 | 1.2645 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7495.065 | 0.5620 | 0.2680 | 1.2645 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7495.065 | 0.2138 | -0.4096 | 1.2645 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7495.065 | 0.0204 | -0.9079 | 1.2645 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7495.065 | 0.0066 | -0.9622 | 1.2645 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7496.065 | 0.9197 | 0.8317 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7496.065 | 0.9331 | 0.8597 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7496.065 | 0.9313 | 0.8559 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7496.065 | 0.9342 | 0.8620 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7496.065 | 0.8192 | 0.6223 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7496.065 | 0.4886 | -0.0570 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7496.065 | 0.1401 | -0.7458 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7496.065 | 0.0165 | -0.9731 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7496.065 | 0.0069 | -0.9892 | 0.9526 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7498.065 | 0.9376 | 0.8940 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7498.065 | 0.9222 | 0.8677 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7498.065 | 0.9577 | 0.9282 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7498.065 | 0.9961 | 0.9933 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7498.065 | 0.9417 | 0.9010 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7498.065 | 0.5700 | 0.2433 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7498.065 | 0.2407 | -0.4000 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7498.065 | 0.0215 | -0.9220 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7498.065 | 0.0124 | -0.9511 | 1.1827 | |
| MDA-MB-175-VII | HR+ | Luminal | Vorinostat | HDAC | HDAC | 0.048 | uM | 7499.065 | 1.0098 | 1.0362 | 0.5419 |