Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
1.2
uM
7450.065
1.0914 1.0735 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
6
uM
7450.065
0.8902 0.9062 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
30
uM
7450.065
0.9269 0.9383 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
150
uM
7450.065
0.5389 0.5496 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
750
uM
7450.065
0.1445 -0.0999 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
3750
uM
7450.065
0.0187 -0.6126 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
18700
uM
7450.065
0.0173 -0.6252 2.4231
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
0.048
uM
7451.065
0.9793 0.9807 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
0.24
uM
7451.065
1.0202 1.0186 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
1.2
uM
7451.065
0.9994 0.9994 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
6
uM
7451.065
0.9343 0.9379 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
30
uM
7451.065
0.8520 0.8566 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
150
uM
7451.065
0.5672 0.5368 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
750
uM
7451.065
0.0423 -0.5401 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
3750
uM
7451.065
0.0139 -0.7254 2.1525
HCC1806
TNBC
Basal A
Vorinostat
HDAC
HDAC
18700
uM
7451.065
0.0126 -0.7378 2.1525
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
0.048
uM
7453.065
0.9726 0.9670 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
0.24
uM
7453.065
1.0397 1.0473 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
1.2
uM
7453.065
1.0086 1.0103 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
6
uM
7453.065
0.9896 0.9875 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
30
uM
7453.065
0.9153 0.8965 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
150
uM
7453.065
0.6725 0.5759 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
750
uM
7453.065
0.3367 0.0401 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
3750
uM
7453.065
0.1629 -0.3275 1.6649
HCC1937
TNBC
Basal A
Vorinostat
HDAC
HDAC
18700
uM
7453.065
0.1399 -0.3863 1.6649