Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7450.065 | 1.0914 | 1.0735 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7450.065 | 0.8902 | 0.9062 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7450.065 | 0.9269 | 0.9383 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7450.065 | 0.5389 | 0.5496 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7450.065 | 0.1445 | -0.0999 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7450.065 | 0.0187 | -0.6126 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7450.065 | 0.0173 | -0.6252 | 2.4231 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 7451.065 | 0.9793 | 0.9807 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7451.065 | 1.0202 | 1.0186 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7451.065 | 0.9994 | 0.9994 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7451.065 | 0.9343 | 0.9379 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7451.065 | 0.8520 | 0.8566 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7451.065 | 0.5672 | 0.5368 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7451.065 | 0.0423 | -0.5401 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7451.065 | 0.0139 | -0.7254 | 2.1525 | |
HCC1806 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7451.065 | 0.0126 | -0.7378 | 2.1525 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 7453.065 | 0.9726 | 0.9670 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7453.065 | 1.0397 | 1.0473 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7453.065 | 1.0086 | 1.0103 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7453.065 | 0.9896 | 0.9875 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7453.065 | 0.9153 | 0.8965 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7453.065 | 0.6725 | 0.5759 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7453.065 | 0.3367 | 0.0401 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7453.065 | 0.1629 | -0.3275 | 1.6649 | |
HCC1937 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7453.065 | 0.1399 | -0.3863 | 1.6649 |