Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7917.018 | 0.9810 | 0.9867 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7917.018 | 1.0476 | 1.0328 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7917.018 | 1.0371 | 1.0256 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7917.018 | 0.4779 | 0.5445 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7917.018 | 0.2244 | 0.1854 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7917.018 | 0.2112 | 0.1606 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7917.018 | 0.2348 | 0.2044 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7917.018 | 0.2391 | 0.2122 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7917.018 | 0.0070 | -0.6483 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9830.006 | 0.9681 | 0.9626 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9830.006 | 0.8153 | 0.7756 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9830.006 | 0.2550 | -0.0980 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9830.006 | 0.2148 | -0.1840 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9830.006 | 0.2437 | -0.1216 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9830.006 | 0.2920 | -0.0239 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9830.006 | 0.1743 | -0.2774 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9830.006 | 0.0060 | -0.8987 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 463 | uM | 9830.006 | 0.0095 | -0.8677 | 1.7160 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7918.018 | 1.0214 | 1.0141 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7918.018 | 0.4770 | 0.5654 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7918.018 | 0.1028 | -0.0581 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7918.018 | 0.0390 | -0.3166 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7918.018 | 0.0555 | -0.2317 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7918.018 | 0.0449 | -0.2838 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7918.018 | 0.0473 | -0.2714 | 3.0213 |