Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7912.018 | 1.0723 | 1.2035 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7912.018 | 0.4663 | -0.3065 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7912.018 | 0.1455 | -0.8624 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7912.018 | 0.1922 | -0.7974 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7912.018 | 0.2697 | -0.6757 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7912.018 | 0.2806 | -0.6573 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7912.018 | 0.0694 | -0.9507 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9759.006 | 1.0324 | 1.0508 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9759.006 | 1.0430 | 1.0673 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9759.006 | 0.1516 | -0.5464 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9759.006 | 0.1844 | -0.4708 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9759.006 | 0.2448 | -0.3389 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9759.006 | 0.3165 | -0.1908 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9759.006 | 0.3219 | -0.1801 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9759.006 | 0.0609 | -0.7787 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 463 | uM | 9759.006 | 0.0148 | -0.9273 | 1.2714 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9797.006 | 1.0260 | 1.1259 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9797.006 | 0.6572 | -0.2645 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9797.006 | 0.3027 | -0.8840 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9797.006 | 0.1815 | -0.9657 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9797.006 | 0.1683 | -0.9714 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9797.006 | 0.1596 | -0.9748 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9797.006 | 0.1130 | -0.9889 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9797.006 | 0.0023 | -1.0000 | 0.4196 | |
| SUM1315MO2 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 463 | uM | 9797.006 | 0.0085 | -1.0000 | 0.4196 |