Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9648.132 | 0.9596 | 0.8879 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9648.132 | 0.6439 | 0.0802 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9648.132 | 1.0027 | 1.0077 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9648.132 | 0.9711 | 0.9196 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9648.132 | 1.0238 | 1.0670 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9648.132 | 0.8520 | 0.5984 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9648.132 | 0.9234 | 0.7888 | 0.7147 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9648.132 | 0.9862 | 0.9615 | 0.7147 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7897.016 | 1.0495 | 1.1370 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7897.016 | 0.9919 | 0.9777 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7897.016 | 0.9413 | 0.8410 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7897.016 | 0.9747 | 0.9311 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7897.016 | 1.0121 | 1.0331 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7897.016 | 0.9780 | 0.9400 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7897.016 | 0.9733 | 0.9271 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7897.016 | 0.8059 | 0.4881 | 0.7300 | ||
| MDA-MB-415 | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7897.016 | 0.0697 | -0.9480 | 0.7300 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7898.016 | 1.0988 | 1.1615 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7898.016 | 0.9713 | 0.9526 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7898.016 | 1.1256 | 1.2049 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7898.016 | 0.9809 | 0.9685 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7898.016 | 1.0763 | 1.1250 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7898.016 | 0.9681 | 0.9472 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7898.016 | 1.0885 | 1.1449 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7898.016 | 0.5510 | 0.2234 | 1.2127 |