Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 7508.074 | 0.9832 | 0.9577 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 7508.074 | 1.0018 | 1.0046 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 7508.074 | 0.9458 | 0.8641 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 7508.074 | 0.9002 | 0.7516 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7508.074 | 0.9016 | 0.7550 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7508.074 | 0.8730 | 0.6849 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7508.074 | 0.8259 | 0.5711 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7508.074 | 0.8050 | 0.5210 | 0.7924 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 7510.074 | 1.0049 | 1.0124 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 7510.074 | 1.0369 | 1.0935 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 7510.074 | 0.9464 | 0.8656 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 7510.074 | 0.7969 | 0.5015 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 7510.074 | 0.8710 | 0.6799 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7510.074 | 0.7196 | 0.3199 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7510.074 | 0.6223 | 0.0988 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7510.074 | 0.4549 | -0.2602 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7510.074 | 0.4094 | -0.3524 | 0.7920 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 7511.074 | 0.9684 | 0.9497 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 7511.074 | 0.9592 | 0.9350 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 7511.074 | 0.9833 | 0.9735 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 7511.074 | 0.9573 | 0.9319 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 7511.074 | 0.8357 | 0.7348 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7511.074 | 0.7283 | 0.5556 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7511.074 | 0.6348 | 0.3951 | 1.2617 | |
| MDA-MB-415 | HR+ | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7511.074 | 0.4532 | 0.0680 | 1.2617 |