Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7545.065 | 0.9265 | 0.8503 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 8 | uM | 7545.065 | 0.4817 | -0.0507 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 40 | uM | 7545.065 | 0.0215 | -0.9602 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 200 | uM | 7545.065 | 0.0214 | -0.9604 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 1000 | uM | 7545.065 | 0.0232 | -0.9570 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 5000 | uM | 7545.065 | 0.0174 | -0.9678 | 0.9803 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7546.065 | 0.9816 | 0.9558 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7546.065 | 0.9868 | 0.9681 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7546.065 | 0.9454 | 0.8692 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7546.065 | 0.8286 | 0.5946 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 8 | uM | 7546.065 | 0.5062 | -0.1194 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 40 | uM | 7546.065 | 0.0522 | -0.9429 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 200 | uM | 7546.065 | 0.0262 | -0.9751 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 1000 | uM | 7546.065 | 0.0186 | -0.9836 | 0.8300 | |
| T47DKBLUC | Unknown | Unknown | Trichostatin A | HDAC | HDAC | 5000 | uM | 7546.065 | 0.0435 | -0.9542 | 0.8300 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7547.065 | 0.9141 | 0.8251 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7547.065 | 0.8217 | 0.6371 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7547.065 | 0.9327 | 0.8628 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7547.065 | 0.8439 | 0.6822 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 8 | uM | 7547.065 | 0.7471 | 0.4856 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 40 | uM | 7547.065 | 0.1817 | -0.6486 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 200 | uM | 7547.065 | 0.1083 | -0.7926 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 1000 | uM | 7547.065 | 0.1122 | -0.7851 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 5000 | uM | 7547.065 | 0.0532 | -0.8996 | 0.9808 | |
| UACC-812 | HER2amp | Luminal | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 10420.065 | 0.9950 | 0.9809 | 0.5232 |