Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7926.018 | 1.0115 | 1.0219 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7926.018 | 1.0253 | 1.0482 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7926.018 | 0.6203 | 0.2693 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7926.018 | 0.6749 | 0.3753 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7926.018 | 0.6233 | 0.2752 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7926.018 | 0.5777 | 0.1860 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7926.018 | 0.5342 | 0.1008 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7926.018 | 0.0357 | -0.9162 | 1.0502 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 9045.018 | 1.0867 | 1.1600 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 9045.018 | 0.8209 | 0.6662 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 9045.018 | 1.1174 | 1.2164 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 9045.018 | 0.5253 | 0.1023 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 9045.018 | 0.2420 | -0.4618 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 9045.018 | 0.2675 | -0.4096 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 9045.018 | 0.2575 | -0.4301 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9045.018 | 0.2969 | -0.3498 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 9045.018 | 0.2573 | -0.4305 | 1.0807 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7931.042 | 1.0664 | 1.0948 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7931.042 | 1.0110 | 1.0159 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7931.042 | 0.9988 | 0.9982 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7931.042 | 1.0017 | 1.0025 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7931.042 | 0.5722 | 0.3376 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7931.042 | 0.4316 | 0.0917 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7931.042 | 0.4483 | 0.1220 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7931.042 | 0.4415 | 0.1095 | 1.3878 |