Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 1.44 | uM | 9254.124 | 1.0140 | 1.0347 | 0.8067 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 7.2 | uM | 9254.124 | 0.9507 | 0.8784 | 0.8067 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.0000184 | uM | 9258.026 | 0.8104 | 0.3769 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.0000922 | uM | 9258.026 | 1.0805 | 1.2949 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.000461 | uM | 9258.026 | 0.9990 | 0.9963 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.0023 | uM | 9258.026 | 0.9998 | 0.9994 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.0115 | uM | 9258.026 | 0.9927 | 0.9740 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.0576 | uM | 9258.026 | 1.0660 | 1.2404 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 0.288 | uM | 9258.026 | 0.9259 | 0.7446 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 1.44 | uM | 9258.026 | 0.8752 | 0.5784 | 0.5632 | |
| HCC1395 | TNBC | Basal B | Trastuzumab | HER2 | ErbB | 7.2 | uM | 9258.026 | 0.8825 | 0.6020 | 0.5632 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0000184 | uM | 9278.026 | 0.9972 | 0.9837 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0000922 | uM | 9278.026 | 0.9617 | 0.7827 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.000461 | uM | 9278.026 | 0.9942 | 0.9657 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0023 | uM | 9278.026 | 0.9352 | 0.6417 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0115 | uM | 9278.026 | 0.9367 | 0.6495 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0576 | uM | 9278.026 | 0.9154 | 0.5416 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.288 | uM | 9278.026 | 0.9519 | 0.7298 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 1.44 | uM | 9278.026 | 0.9089 | 0.5094 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 7.2 | uM | 9278.026 | 0.8071 | 0.0640 | 0.3395 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0000184 | uM | 10019.124 | 1.0376 | 1.1426 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0000922 | uM | 10019.124 | 1.0770 | 1.2973 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.000461 | uM | 10019.124 | 1.0574 | 1.2196 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0023 | uM | 10019.124 | 0.9494 | 0.8153 | 0.5356 | |
| HCC1419 | HER2amp | Luminal | Trastuzumab | HER2 | ErbB | 0.0115 | uM | 10019.124 | 0.9796 | 0.9245 | 0.5356 |