| HMS LINCS ID:
|
80076
|
| Name:
|
Trastuzumab
|
| Alternative Names:
|
Herceptin; rhuMAb HER2
|
| Clone Name:
|
huMAb4D5-8
|
| Resource Identification Initiative ID:
|
|
| LINCS ID:
|
|
| Type:
|
engineered
|
| Nominal Protein Target(s):
|
erbB-2
|
| Nominal Protein Target HMS LINCS ID(s):
|
200509
|
| Nominal Non-protein Target:
|
|
| Organism of Nominal Target:
|
Homo sapiens
|
| Other Target Information:
|
selectively binds with high affinity to the extracellular domain of the human HER2 (source: Genentech)
|
| Other Human Protein Target HMS LINCS ID(s):
|
|
| Immunogen:
|
|
| Immunogen Sequence:
|
|
| Fc Domain Source Species:
|
human
|
| Clonality:
|
monoclonal
|
| Fc Domain Isotype:
|
IgG1
|
| Source Organism for Production:
|
Chinese Hamster Ovary cells
|
| Production Details:
|
humanized IgG1 kappa monoclonal antibody derived from mouse monoclonal antibody 4D5; produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) culture containing the antibiotic gentamicin. (source: Genentech)
|
| Conjugate or Label:
|
|
| Labeling Details:
|
|
| Relevant Citations:
|
|
| Comments:
|
|
| Date Publicly Available:
|
2016-09-16
|
| Most Recent Update:
|
2016-09-16
|