Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7515.093 | 0.8880 | 0.8334 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7515.093 | 0.8790 | 0.8197 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 7515.093 | 0.8949 | 0.8439 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 7515.093 | 0.8985 | 0.8492 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 7515.093 | 0.8247 | 0.7368 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 7515.093 | 0.7385 | 0.6019 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 7515.093 | 0.7970 | 0.6939 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7516.093 | 0.8952 | 0.8385 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7516.093 | 0.8831 | 0.8195 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7516.093 | 0.9576 | 0.9351 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7516.093 | 0.9315 | 0.8950 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 7516.093 | 0.9561 | 0.9328 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 7516.093 | 0.9294 | 0.8917 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 7516.093 | 0.9083 | 0.8589 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 7516.093 | 0.7180 | 0.5545 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 7516.093 | 0.6234 | 0.3961 | 1.3148 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7517.093 | 0.9587 | 0.9441 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7517.093 | 1.0077 | 1.0104 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7517.093 | 0.9157 | 0.8849 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7517.093 | 0.9651 | 0.9528 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 7517.093 | 1.0125 | 1.0168 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 7517.093 | 0.9266 | 0.9001 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 7517.093 | 0.9282 | 0.9023 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 7517.093 | 0.7273 | 0.6145 | 1.4869 | |
| MDA-MB-453 | TNBC | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 7517.093 | 0.7103 | 0.5890 | 1.4869 |