Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF 10F
NM
-
Temsirolimus
MTOR
MTOR
0.213
uM
12254.144
0.6339 0.5702 1.8842
MCF 10F
NM
-
Temsirolimus
MTOR
MTOR
1.07
uM
12254.144
0.5724 0.4874 1.8842
MCF 10F
NM
-
Temsirolimus
MTOR
MTOR
5.33
uM
12254.144
0.6391 0.5770 1.8842
MCF 10F
NM
-
Temsirolimus
MTOR
MTOR
26.7
uM
12254.144
0.5181 0.4107 1.8842
MCF 10F
NM
-
Temsirolimus
MTOR
MTOR
133
uM
12254.144
0.1403 -0.2947 1.8842
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.000341
uM
10817.144
0.9620 0.9477 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.00171
uM
10817.144
0.9622 0.9480 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.00853
uM
10817.144
0.9837 0.9776 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.0427
uM
10817.144
0.9516 0.9333 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.213
uM
10817.144
0.9163 0.8841 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
1.07
uM
10817.144
0.9440 0.9227 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
5.33
uM
10817.144
0.8583 0.8017 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
26.7
uM
10817.144
0.1926 -0.3507 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
133
uM
10817.144
0.0077 -0.9282 1.4640
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.000341
uM
12365.168
1.0244 1.0221 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.00171
uM
12365.168
0.9404 0.9447 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.00853
uM
12365.168
1.0225 1.0204 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.0427
uM
12365.168
0.9259 0.9309 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
0.213
uM
12365.168
0.8037 0.8102 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
1.07
uM
12365.168
0.8186 0.8254 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
5.33
uM
12365.168
0.7761 0.7816 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
26.7
uM
12365.168
0.2713 0.1029 2.1914
MCF12A
NM
Basal B
Temsirolimus
MTOR
MTOR
133
uM
12365.168
0.0095 -0.7608 2.1914
MCF7
HR+
Luminal
Temsirolimus
MTOR
MTOR
0.000341
uM
10997.144
0.9386 0.9030 1.2750
MCF7
HR+
Luminal
Temsirolimus
MTOR
MTOR
0.00171
uM
10997.144
0.9884 0.9819 1.2750