Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10F | NM | - | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12254.144 | 0.6339 | 0.5702 | 1.8842 | |
MCF 10F | NM | - | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12254.144 | 0.5724 | 0.4874 | 1.8842 | |
MCF 10F | NM | - | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12254.144 | 0.6391 | 0.5770 | 1.8842 | |
MCF 10F | NM | - | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12254.144 | 0.5181 | 0.4107 | 1.8842 | |
MCF 10F | NM | - | Temsirolimus | MTOR | MTOR | 133 | uM | 12254.144 | 0.1403 | -0.2947 | 1.8842 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10817.144 | 0.9620 | 0.9477 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10817.144 | 0.9622 | 0.9480 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10817.144 | 0.9837 | 0.9776 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10817.144 | 0.9516 | 0.9333 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10817.144 | 0.9163 | 0.8841 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10817.144 | 0.9440 | 0.9227 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10817.144 | 0.8583 | 0.8017 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10817.144 | 0.1926 | -0.3507 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 10817.144 | 0.0077 | -0.9282 | 1.4640 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12365.168 | 1.0244 | 1.0221 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12365.168 | 0.9404 | 0.9447 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12365.168 | 1.0225 | 1.0204 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12365.168 | 0.9259 | 0.9309 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12365.168 | 0.8037 | 0.8102 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12365.168 | 0.8186 | 0.8254 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12365.168 | 0.7761 | 0.7816 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12365.168 | 0.2713 | 0.1029 | 2.1914 | |
MCF12A | NM | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 12365.168 | 0.0095 | -0.7608 | 2.1914 | |
MCF7 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10997.144 | 0.9386 | 0.9030 | 1.2750 | |
MCF7 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10997.144 | 0.9884 | 0.9819 | 1.2750 |