Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.0427	uM	12224.144	0.9166	0.8365	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.213	uM	12224.144	0.8793	0.7633	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	1.07	uM	12224.144	0.8110	0.6291	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	5.33	uM	12224.144	0.8006	0.6085	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	26.7	uM	12224.144	0.7268	0.4631	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	133	uM	12224.144	0.3207	-0.3435	1.0210
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	0.000341	uM	10880.144	0.8926	0.8811	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	0.00171	uM	10880.144	0.8818	0.8687	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	0.00853	uM	10880.144	0.7539	0.7173	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	0.0427	uM	10880.144	0.5951	0.5115	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	0.213	uM	10880.144	0.5213	0.4073	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	1.07	uM	10880.144	0.4947	0.3680	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	5.33	uM	10880.144	0.4744	0.3375	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	26.7	uM	10880.144	0.2917	0.0288	1.8532
AU565	HER2amp	Luminal	Temsirolimus	MTOR	MTOR	133	uM	10880.144	0.0170	-0.7781	1.8532
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	0.000341	uM	10581.144	0.8132	0.6846	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	0.00171	uM	10581.144	0.6425	0.3854	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	0.00853	uM	10581.144	0.6544	0.4066	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	0.0427	uM	10581.144	0.6989	0.4856	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	0.213	uM	10581.144	0.6974	0.4829	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	1.07	uM	10581.144	0.6300	0.3629	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	5.33	uM	10581.144	0.5665	0.2479	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	26.7	uM	10581.144	0.5628	0.2411	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	133	uM	10581.144	0.0458	-0.8452	1.2048
BT-20	TNBC	Basal A	Temsirolimus	MTOR	MTOR	0.000341	uM	11854.144	0.9018	0.8483	1.3102

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)