Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10874.148 | 1.0758 | 1.2210 | 0.6972 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10874.148 | 1.0072 | 1.0208 | 0.6972 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10874.148 | 0.9777 | 0.9363 | 0.6972 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10874.148 | 0.9792 | 0.9407 | 0.6972 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10874.148 | 0.7938 | 0.4360 | 0.6972 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10874.148 | 1.0666 | 1.1939 | 0.6972 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12220.135 | 0.9134 | 0.7423 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12220.135 | 0.8605 | 0.5908 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12220.135 | 0.8840 | 0.6574 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12220.135 | 0.9128 | 0.7405 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12220.135 | 0.8824 | 0.6530 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12220.135 | 0.9250 | 0.7762 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12220.135 | 0.8746 | 0.6308 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12220.135 | 0.8291 | 0.5033 | 0.6564 | |
| MX1 | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12220.135 | 0.7426 | 0.2711 | 0.6564 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11851.135 | 0.9718 | 0.9556 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11851.135 | 1.0527 | 1.0824 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11851.135 | 0.9467 | 0.9157 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11851.135 | 1.0662 | 1.1034 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11851.135 | 0.9961 | 0.9938 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11851.135 | 0.9656 | 0.9456 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11851.135 | 1.0692 | 1.1080 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11851.135 | 0.9079 | 0.8537 | 1.2721 | |
| SK-BR-3 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11851.135 | 0.6654 | 0.4519 | 1.2721 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10875.148 | 1.0761 | 1.2026 | 0.7605 |