Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11850.135 | 0.9900 | 0.9895 | 1.9060 | |
| HCC38 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11850.135 | 0.9215 | 0.9160 | 1.9060 | |
| HCC38 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11850.135 | 0.9847 | 0.9839 | 1.9060 | |
| HCC38 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11850.135 | 0.9331 | 0.9286 | 1.9060 | |
| HCC38 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11850.135 | 0.8632 | 0.8514 | 1.9060 | |
| HCC38 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11850.135 | 0.5338 | 0.4387 | 1.9060 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10873.148 | 0.9870 | 0.9786 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10873.148 | 0.9561 | 0.9275 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10873.148 | 1.0189 | 1.0311 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10873.148 | 0.9524 | 0.9214 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10873.148 | 1.0844 | 1.1379 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10873.148 | 0.8873 | 0.8125 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10873.148 | 0.9151 | 0.8591 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10873.148 | 0.9792 | 0.9658 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10873.148 | 0.9482 | 0.9143 | 1.2150 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12400.135 | 0.9973 | 0.9958 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12400.135 | 0.9675 | 0.9496 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12400.135 | 0.9849 | 0.9767 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12400.135 | 0.9762 | 0.9632 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12400.135 | 0.9756 | 0.9623 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12400.135 | 1.0045 | 1.0070 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12400.135 | 1.0101 | 1.0155 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12400.135 | 1.0135 | 1.0208 | 1.2966 | |
| HCC70 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12400.135 | 0.8090 | 0.6983 | 1.2966 | |
| Hs 578T | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10694.148 | 1.0084 | 1.0068 | 2.4626 |