Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 11855.159 | 0.9657 | 0.8931 | 0.6347 | |
| BT-483 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 11855.159 | 0.7244 | 0.2034 | 0.6347 | |
| BT-483 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 11855.159 | 0.5898 | -0.1295 | 0.6347 | |
| BT-483 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 11855.159 | 0.4582 | -0.4152 | 0.6347 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12305.152 | 0.9756 | 0.9834 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12305.152 | 1.0150 | 1.0100 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12305.152 | 1.0058 | 1.0039 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12305.152 | 0.9703 | 0.9798 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12305.152 | 0.9765 | 0.9841 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12305.152 | 0.8211 | 0.8716 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 1.33 | uM | 12305.152 | 0.1128 | -0.0409 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 6.67 | uM | 12305.152 | 0.0411 | -0.3171 | 2.9694 | |
| BT-549 | TNBC | Basal B | TCS 2312 | CHK1 | CHK | 33.3 | uM | 12305.152 | 0.0395 | -0.3266 | 2.9694 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10473.14 | 0.9321 | 0.8957 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10473.14 | 0.9225 | 0.8808 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10473.14 | 0.9683 | 0.9516 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10473.14 | 0.9344 | 0.8992 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10473.14 | 0.9145 | 0.8684 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10473.14 | 0.8975 | 0.8418 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10473.14 | 0.6316 | 0.4093 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10473.14 | 0.1545 | -0.5178 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10473.14 | 0.1071 | -0.6353 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10755.152 | 0.9970 | 0.9897 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10755.152 | 0.9369 | 0.7894 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10755.152 | 0.9880 | 0.9593 | 0.5859 |