Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 6.67 | uM | 9860.002 | 0.2554 | -0.1600 | 1.5734 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 33.3 | uM | 9860.002 | 0.2672 | -0.1356 | 1.5734 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.0000853 | uM | 13009.002 | 1.0611 | 1.0903 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.000427 | uM | 13009.002 | 0.9827 | 0.9742 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.00213 | uM | 13009.002 | 1.0282 | 1.0419 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.0107 | uM | 13009.002 | 0.8734 | 0.8080 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.0533 | uM | 13009.002 | 0.4090 | 0.0271 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.267 | uM | 13009.002 | 0.3779 | -0.0317 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 1.33 | uM | 13009.002 | 0.3583 | -0.0693 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 6.67 | uM | 13009.002 | 0.3457 | -0.0938 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 33.3 | uM | 13009.002 | 0.3495 | -0.0865 | 1.3417 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.0000853 | uM | 13062.002 | 1.0552 | 1.0663 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.000427 | uM | 13062.002 | 1.0170 | 1.0206 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.00213 | uM | 13062.002 | 1.0548 | 1.0658 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.0107 | uM | 13062.002 | 0.7987 | 0.7448 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.0533 | uM | 13062.002 | 0.3864 | 0.1227 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 0.267 | uM | 13062.002 | 0.3247 | 0.0103 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 1.33 | uM | 13062.002 | 0.3413 | 0.0413 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 6.67 | uM | 13062.002 | 0.2995 | -0.0381 | 1.6470 | |
| SUM229PE | TNBC | - | Taxol | TUBB | TUBB | 33.3 | uM | 13062.002 | 0.3171 | -0.0042 | 1.6470 | |
| SUM52PE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9878.002 | 1.1139 | 1.1672 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9878.002 | 1.0013 | 1.0019 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9878.002 | 0.9961 | 0.9942 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9878.002 | 0.4751 | 0.1495 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9878.002 | 0.2538 | -0.2792 | 1.3437 |