Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 10139.002 | 0.3853 | -0.3304 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 10139.002 | 0.2768 | -0.5418 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 10139.002 | 0.2957 | -0.5059 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 10139.002 | 0.2844 | -0.5274 | 0.8715 | |
| SUM1315MO2 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 10139.002 | 0.2679 | -0.5588 | 0.8715 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 9830.002 | 1.1673 | 1.1673 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 9830.002 | 1.0867 | 1.0883 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 9830.002 | 1.0895 | 1.0911 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 9830.002 | 0.3819 | 0.2130 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 9830.002 | 0.2654 | 0.0041 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 9830.002 | 0.2002 | -0.1327 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 9830.002 | 0.1827 | -0.1730 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 9830.002 | 0.1718 | -0.1990 | 1.9252 | |
| SUM149PT | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 9830.002 | 0.1830 | -0.1722 | 1.9252 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 7918.002 | 0.8930 | 0.9218 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 7918.002 | 0.8639 | 0.8995 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 7918.002 | 0.9390 | 0.9561 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 7918.002 | 0.7894 | 0.8401 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 7918.002 | 0.1179 | -0.0585 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 7918.002 | 0.0696 | -0.2179 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 7918.002 | 0.0533 | -0.2880 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 7918.002 | 0.0791 | -0.1819 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 7918.002 | 0.0580 | -0.2669 | 2.8377 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 9844.002 | 1.0853 | 1.0676 | 2.4608 | |
| SUM159PT | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 9844.002 | 0.9987 | 0.9989 | 2.4608 |