Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7442.096 | 0.9109 | 0.7708 | 0.7665 | ||
| HCC1428 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7442.096 | 0.8052 | 0.5074 | 0.7665 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7451.096 | 0.9592 | 0.9622 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7451.096 | 0.9595 | 0.9625 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7451.096 | 0.9769 | 0.9788 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7451.096 | 1.0055 | 1.0050 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7451.096 | 0.9812 | 0.9827 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7451.096 | 0.9212 | 0.9263 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7451.096 | 0.8796 | 0.8859 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7451.096 | 0.7887 | 0.7941 | 2.1851 | ||
| HCC1806 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7451.096 | 0.7328 | 0.7347 | 2.1851 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7462.096 | 1.0433 | 1.2563 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7462.096 | 0.9815 | 0.8967 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7462.096 | 1.0259 | 1.1512 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7462.096 | 1.0194 | 1.1123 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7462.096 | 0.9857 | 0.9196 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7462.096 | 0.9402 | 0.6779 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7462.096 | 0.7658 | -0.0642 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7462.096 | 0.8282 | 0.1698 | 0.3514 | ||
| HCC2185 | TNBC | Luminal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7462.096 | 0.7763 | -0.0269 | 0.3514 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7466.096 | 1.0004 | 1.0010 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7466.096 | 0.9445 | 0.8805 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7466.096 | 0.9828 | 0.9629 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7466.096 | 0.9744 | 0.9448 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7466.096 | 1.0169 | 1.0364 | 0.9269 |