Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7466.096 | 0.9620 | 0.9182 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7466.096 | 0.8977 | 0.7803 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7466.096 | 0.9333 | 0.8565 | 0.9269 | ||
| HCC3153 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7466.096 | 0.9130 | 0.8129 | 0.9269 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7468.096 | 0.9629 | 0.9524 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7468.096 | 0.9727 | 0.9650 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7468.096 | 0.9690 | 0.9602 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7468.096 | 0.9461 | 0.9306 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7468.096 | 0.9732 | 0.9656 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7468.096 | 0.9643 | 0.9542 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7468.096 | 1.0008 | 1.0010 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7468.096 | 0.8935 | 0.8614 | 1.5683 | ||
| HCC38 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7468.096 | 0.8893 | 0.8558 | 1.5683 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7470.096 | 1.0218 | 1.0455 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7470.096 | 0.9581 | 0.9125 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7470.096 | 1.0073 | 1.0152 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7470.096 | 0.9666 | 0.9302 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7470.096 | 1.0100 | 1.0208 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7470.096 | 0.8736 | 0.7367 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7470.096 | 0.7952 | 0.5743 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7470.096 | 0.6335 | 0.2416 | 0.9576 | ||
| HCC70 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7470.096 | 0.5180 | 0.0063 | 0.9576 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7485.096 | 1.0257 | 1.0140 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7485.096 | 0.9441 | 0.9685 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7485.096 | 1.0830 | 1.0445 | 3.6265 |