Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 10473.141 | 0.8097 | 0.6960 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 66.7 | uM | 10473.141 | 0.7277 | 0.5604 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 10755.153 | 0.9935 | 0.9827 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10755.153 | 0.8884 | 0.7070 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10755.153 | 1.0177 | 1.0475 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10755.153 | 0.9366 | 0.8321 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10755.153 | 0.9894 | 0.9717 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.267 | uM | 10755.153 | 0.9193 | 0.7870 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 1.33 | uM | 10755.153 | 0.9756 | 0.9350 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 6.67 | uM | 10755.153 | 0.8147 | 0.5202 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 33.3 | uM | 10755.153 | 0.6818 | 0.1978 | 0.7471 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000171 | uM | 12070.158 | 0.9517 | 0.9140 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000853 | uM | 12070.158 | 1.0066 | 1.0117 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00427 | uM | 12070.158 | 0.9623 | 0.9328 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0213 | uM | 12070.158 | 1.0634 | 1.1122 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.107 | uM | 12070.158 | 1.0359 | 1.0637 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.533 | uM | 12070.158 | 0.9541 | 0.9182 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 12070.158 | 0.8773 | 0.7803 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 12070.158 | 1.0193 | 1.0343 | 1.1252 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 66.7 | uM | 12070.158 | 0.8900 | 0.8032 | 1.1252 | |
| HCC1143 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.000171 | uM | 12112.158 | 1.0032 | 1.0035 | 1.8430 | |
| HCC1143 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.000853 | uM | 12112.158 | 0.9175 | 0.9087 | 1.8430 | |
| HCC1143 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.00427 | uM | 12112.158 | 1.0127 | 1.0138 | 1.8430 | |
| HCC1143 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.0213 | uM | 12112.158 | 0.9466 | 0.9413 | 1.8430 | |
| HCC1143 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.107 | uM | 12112.158 | 0.9101 | 0.9004 | 1.8430 |