Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 5901.069 | 1.0277 | 1.0327 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 5901.069 | 0.9917 | 0.9901 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 5901.069 | 0.9272 | 0.9122 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 5901.069 | 0.7709 | 0.7138 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 5901.069 | 0.6529 | 0.5528 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 5901.069 | 0.6065 | 0.4864 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 5901.069 | 0.5835 | 0.4526 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 5901.069 | 0.5457 | 0.3959 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 5901.069 | 0.5138 | 0.3469 | 1.6847 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 9035.068 | 0.9258 | 0.9292 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 9035.068 | 0.9694 | 0.9711 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 9035.068 | 0.6443 | 0.6285 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 9035.068 | 0.5440 | 0.5047 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 9035.068 | 0.5222 | 0.4761 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 9035.068 | 0.4933 | 0.4374 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 9035.068 | 0.5449 | 0.5058 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 9035.068 | 0.5208 | 0.4743 | 2.1391 | |
AU565 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 167 | uM | 9035.068 | 0.3671 | 0.2520 | 2.1391 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 5902.069 | 1.0019 | 1.0033 | 1.1199 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.000427 | uM | 5902.069 | 0.9773 | 0.9595 | 1.1199 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.00213 | uM | 5902.069 | 0.8906 | 0.8034 | 1.1199 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0107 | uM | 5902.069 | 0.7491 | 0.5453 | 1.1199 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0533 | uM | 5902.069 | 0.7012 | 0.4567 | 1.1199 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.267 | uM | 5902.069 | 0.7027 | 0.4596 | 1.1199 | |
BT-20 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 1.33 | uM | 5902.069 | 0.6922 | 0.4401 | 1.1199 |