Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.0000853
uM
5901.069
1.0277 1.0327 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.000427
uM
5901.069
0.9917 0.9901 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.00213
uM
5901.069
0.9272 0.9122 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.0107
uM
5901.069
0.7709 0.7138 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.0533
uM
5901.069
0.6529 0.5528 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.267
uM
5901.069
0.6065 0.4864 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
1.33
uM
5901.069
0.5835 0.4526 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
6.67
uM
5901.069
0.5457 0.3959 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
33.3
uM
5901.069
0.5138 0.3469 1.6847
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.000427
uM
9035.068
0.9258 0.9292 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.00213
uM
9035.068
0.9694 0.9711 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.0107
uM
9035.068
0.6443 0.6285 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.0533
uM
9035.068
0.5440 0.5047 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
0.267
uM
9035.068
0.5222 0.4761 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
1.33
uM
9035.068
0.4933 0.4374 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
6.67
uM
9035.068
0.5449 0.5058 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
33.3
uM
9035.068
0.5208 0.4743 2.1391
AU565
HER2amp
Luminal
Sirolimus
MTOR
MTOR
167
uM
9035.068
0.3671 0.2520 2.1391
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
0.0000853
uM
5902.069
1.0019 1.0033 1.1199
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
0.000427
uM
5902.069
0.9773 0.9595 1.1199
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
0.00213
uM
5902.069
0.8906 0.8034 1.1199
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
0.0107
uM
5902.069
0.7491 0.5453 1.1199
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
0.0533
uM
5902.069
0.7012 0.4567 1.1199
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
0.267
uM
5902.069
0.7027 0.4596 1.1199
BT-20
TNBC
Basal A
Sirolimus
MTOR
MTOR
1.33
uM
5902.069
0.6922 0.4401 1.1199