Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 1.33 | uM | 9860.019 | 0.8300 | 0.7915 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 6.67 | uM | 9860.019 | 0.6934 | 0.6110 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 33.3 | uM | 9860.019 | 0.7897 | 0.7397 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 167 | uM | 9860.019 | 0.7552 | 0.6943 | 1.6927 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7538.016 | 0.6979 | 0.4345 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7538.016 | 0.8599 | 0.7397 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7538.016 | 0.7349 | 0.5046 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7538.016 | 0.7563 | 0.5452 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7538.016 | 0.7888 | 0.6063 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7538.016 | 0.7080 | 0.4537 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7538.016 | 0.7717 | 0.5741 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7538.016 | 0.4704 | -0.0036 | 1.0824 | |
| SUM44PE | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7538.016 | 0.6115 | 0.2696 | 1.0824 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7540.016 | 0.9711 | 0.9389 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7540.016 | 1.0201 | 1.0425 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7540.016 | 0.9845 | 0.9673 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7540.016 | 0.9217 | 0.8347 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7540.016 | 1.0901 | 1.1910 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7540.016 | 0.9154 | 0.8215 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7540.016 | 1.0438 | 1.0927 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7540.016 | 0.4972 | -0.0449 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7540.016 | 0.4910 | -0.0574 | 0.9455 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7923.016 | 0.7383 | 0.2336 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7923.016 | 0.6358 | -0.0276 | 0.6280 | |
| SUM52PE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7923.016 | 0.5651 | -0.1939 | 0.6280 |