Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7436.074 | 0.9577 | 0.9302 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7436.074 | 0.9363 | 0.8947 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7436.074 | 0.9363 | 0.8947 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7436.074 | 0.6566 | 0.4157 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7436.074 | 0.6566 | 0.4157 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7436.074 | 0.1162 | -0.6586 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7436.074 | 0.1162 | -0.6586 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7436.074 | 0.0607 | -0.7997 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7436.074 | 0.0607 | -0.7997 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7436.074 | 0.0435 | -0.8477 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7436.074 | 0.0435 | -0.8477 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7436.074 | 0.0496 | -0.8305 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7436.074 | 0.0496 | -0.8305 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7436.074 | 0.0581 | -0.8070 | 1.2173 | |
| HCC1395 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7436.074 | 0.0581 | -0.8070 | 1.2173 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7437.074 | 1.0334 | 1.1835 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7437.074 | 1.0334 | 1.1835 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7437.074 | 1.0128 | 1.0691 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7437.074 | 1.0128 | 1.0691 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7437.074 | 1.0371 | 1.2044 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7437.074 | 1.0371 | 1.2044 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7437.074 | 0.7199 | -0.1680 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7437.074 | 0.7199 | -0.1680 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7437.074 | 0.2744 | -0.9366 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7437.074 | 0.2744 | -0.9366 | 0.3747 |